Research

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Scientific Research

The CIOCD promotes national and international clinical and research collaboration among OCD experts, and advancement of scientific research designed to inform best practice specialized treatment. Research supported by the CIOCD focuses on improvement in accessibility of timely evidence based specialized treatments for OCD and related disorders throughout the lifespan and on specialized interventions to improve rates of recovery from illness. Ongoing research and recent publications by CIOCD committee members are available on request.

Enclosed below are select publications in this field, some by the CIOCD International OCD Task Force (ATF*) and others in which CIOCD had no involvement.

Aggarwal, N. K., Sadaghiyani, S., Kananian, S., Lam, P., Messner, G., Marincowitz, C., Narayan, M., Luciano, A. C., van Balkom, A. J. L. M., Hezel, D., Lochner, C., Shavitt, R. G., van den Heuvel, O. A., Simpson, B., & Lewis-Fernández, R. (2024). Patient Perceptions of Illness Causes and Treatment Preferences for Obsessive-Compulsive Disorder: A Mixed-Methods Study. Culture, Medicine and Psychiatry, 10.1007/s11013-024-09865-5. Advance online publication. https://doi.org/10.1007/s11013-024-09865-5

Asnaani, A., Kaczkurkin, A. N., Alpert, E., McLean, C. P., Simpson, H. B., & Foa, E. (2017). The effect of treatment on quality of life and functioning in OCD. Comprehensive Psychiatry, 73, 7-14.

*ATF Five Paper Special Issue: Knowledge and Competency Standards for Specialized Treatments for OCD Through the Lifespan, Psychiatry Research, 2021. https://www.sciencedirect.com/journal/psychiatry-research/special-issue/10QR7D2XHJ0

Bruin, W. B., Abe, Y., Alonso, P., Anticevic, A., Backhausen, L. L., Balachander, S., … Van Wingen, G. A. (2023). The functional connectome in obsessive-compulsive disorder: Resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium. Molecular Psychiatry, 28(10), 4307-4319. https://doi.org/10.1038/s41380-023-02077-0

Cervin, M., McGuire, J. F., D’Souza, J. M., De Nadai, A. S., Aspvall, K., Goodman, W. K., Andrén, P., Schneider, S. C., Geller, D. A., Mataix-Cols, D., & Storch, E. A. (2024). Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis. J Child Psychol Psychiatry, 65(5), 594-609. https://doi.org/10.1111/jcpp.13934 

Elsner, B., Jacobi, T., Kischkel, E., Schulze, D., & Reuter, B. (2022). Mechanisms of exposure and response prevention in obsessive-compulsive disorder: Effects of habituation and expectancy violation on short-term outcome in cognitive behavioral therapy. BMC Psychiatry, Vol 22, 2022, ArtID 66, 22.

*Fineberg, NA., Reghunandanan S., Simpson HB., Phillips, K., Richter, P., Matthews K , Stein DS,  Sareen J., Brown A., & Sookman, D. (2015). Obsessive Compulsive Disorder (OCD): practical strategies for pharmacological and somatic treatment in adults, Psychiatry Research, 227, 114-125.

Flygare, O., Andersson, E., Ringberg, H., Hellstadius, A. C., Edbacken, J., Enander, J., Dahl, M., Aspvall, K., Windh, I., Russell, A., Mataix-Cols, D. & Rück, C. (2019). Adapted cognitive behavior therapy for obsessive–compulsive disorder with co-occurring autism spectrum disorder: A clinical effectiveness study. Autism, 1362361319856974.

*Franklin, M. E., Dingfelder, H. E., Freeman, J. B., Ivarsson, T., Heyman, I., Sookman, D., McKay, D., Storch, E. A., & March, J. (2015). Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder: Empirical Review and Clinical Recommendations, Psychiatry Research, 227, 78-92.

*Ivarsson, T., Skarphedinsson, G., Kornør, H., Axelsdottir, B., Biedilæ, S, Heyman, I., Asbahr, F., Hove Thomsen, P., Fineberg, N., & March, J. (2015). The place of and evidence for serotonin reuptake inhibitors (SRIs) in obsessive compulsive disorder (OCD) in children and adolescents: views based on a systematic review and meta-analysis. Psychiatry Research, 227(1): 93–103.

Ivarsson, T., Jensen, S., Hojgaard, D. R., Hybel, K. A., Torp, N. C., Melin, K., Nissen, J. B., Weidle, B., Thomsen, P. H., Dahl, K., & Skarphedinsson, G. (2023). Remission and relapse across three years in pediatric obsessive-compulsive disorder following evidence-based treatments. Journal of the American Academy of Child & Adolescent Psychiatry.

Kathmann, N., Jacobi, T., Elsner, B., & Reuter, B. (2022). Effectiveness of Individual Cognitive-Behavioral Therapy and Predictors of Outcome in Adult Patients with Obsessive-Compulsive Disorder. Psychother Psychosom, 91(2), 123-135. https://doi.org/10.1159/000520454 

Lissemore, J., Sookman, D., Gravel, P., Berney, A., Barsoum, A., Diksic, M., Nordahl, T. E., Pinard, G., Sibon, I., Cottraux, J., Leyton, M., & Benkelfat, C. (2018). Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline, Transl. Psychiatry, 8, 82. doi: 10.1038/s41398-018-0128-4.

Lundström, L., Ivanova, E., Mataix-Cols, D., Flygare, O., Cervin, M., Rück, C., & Andersson, E. (2024). Incompleteness as a clinical characteristic and predictor of treatment outcome in obsessive-compulsive disorder. Journal of Obsessive-Compulsive and Related Disorders, 100880.

Maloney, G., Koh, G., Roberts, S., & Pittenger, C. (2019). Imagery rescripting as an adjunct clinical intervention for obsessive compulsive disorder. J Anxiety Disord. 66:102110. doi: 10.1016/j.janxdis.2019.102110.

Öst, L.-G., Enebrink, P., Finnes, A., Ghaderi, A., Havnen, A., Kvale, G., Salomonsson, S., & Wergeland, G. J. (2022). Cognitive behavior therapy for obsessive-compulsive disorder in routine clinical care: A systematic review and meta-analysis. Behaviour Research and Therapy, 159, 104170. 

*Piacentini, J., Wu, M., Rozenman, M., Bennett, S., McGuire, J., Nadeau, J., Lewin, A., Sookman, D., Bergman, R. L., Storch, E. A., & Peris, T. (2021). Knowledge and competency standards for specialized cognitive behavior therapy for pediatric obsessive-compulsive disorder. Psychiatry Research, 299, 113854.

*Pittenger, C., Brennan, B. P., Koran, L., Mathews, C. A., Nestadt, G., Pato, M., Phillips, K. A., Rodriguez, C. I., Simpson, H. B., Skapinakis, P., Stein, D. J., & Storch, E. A. (2021). Specialty knowledge and competency standards for pharmacotherapy for adult obsessive-compulsive disorder. Psychiatry Research, 300, 113853.

Phillips K. A. (2017). Classification of body dysmorphic disorder and relevance for patient care. In K. A. Phillips (Ed.), Body Dysmorphic Disorder: Advances in Research and Clinical Practice. New York, NY: Oxford University Press.

Phillips K. A. (2019). Body dysmorphic disorder. American Society of Clinical Psychopharmacology Model Psychopharmacology Curriculum, for Training Directors and Teachers of Psychopharmacology in Psychiatric Residency Programs, 10th Edition. Brentwood, TN: ASCP.

Simkin, V., Hodsoll, J., & Veale, D. (2022). The relationship between symptoms of obsessive compulsive disorder and depression during therapy: A random intercept cross-lagged panel model. Journal of Behavior Therapy and Experimental Psychiatry, 76, 101748.

Simpson, H. B., Foa, E. B., Liebowitz, M. R., Ledley, D. R., Huppert, J. D., Cahill, S., Vermes, D., Schmidt, A. B., Hembree, E., Franklin, M., Campeas, R., Hahn, C. G., & Petkova E. (2008). A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorder. American Journal of Psychiatry, 165, 5, 621-630.

Snorrason, I., Jaroszewski, A. C., Greenberg, J. L., Weingarden, H., Summers, B. J., Fang, A., Hoeppner, S. S., Hollander, E., Goodman, W. K., Phillips, K. A., & Wilhelm, S. (2024). Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder: Factor Structure and Construct Validity of Subfactors. Journal of Obsessive-Compulsive and Related Disorders, 100881.

*Sookman, D. & Fineberg, N. (2015). Specialized Psychological and Pharmacological Treatments for Obsessive-Compulsive Disorder throughout the lifespan: A special series by the Accreditation Task Force (ATF) of The Canadian Institute for Obsessive Compulsive Disorders (CIOCD, www.ciocd.ca), Psychiatry Research, 227, 74-77.

*Sookman, D., Phillips, K. A., Anholt, G. E., Bhar, S., Bream, V., Challacombe, F. L., Coughtrey, A., Craske, M. G., Foa, E., Gagné, J.-P., Huppert, J. D., Jacobi, D., Lovell, K., McLean, C. P., Neziroglu, F., Pedley, R., Perrin, S., Pinto, A., Pollard, C. A., Radomsky, A. S., & Veale, D. (2021). Knowledge and competency standards for specialized cognitive behavior therapy for adult obsessive-compulsive disorder. Psychiatry Research, 303, 113752.

*Sookman, D., Phillips, K.A., Mataix-Cols, D., & Veale, D. (2021). Introduction to knowledge and competency standards for specialized treatments for obsessive-compulsive disorder throughout the lifespan: phase two series by the International Accreditation Task Force of The Canadian Institute for Obsessive Compulsive Disorders (CIOCD, www.ciocd.ca). Psychiatry Res. 298. 113753. https://doi.org/10.1016/j.psychres.2021.113753.

Taylor, S., McKay, D., Miguel, E., De Mathis, M., Andrade, C., Ahuja, N., Sookman, D., Jun Soo Kwon, J. S., Huh, M. G., Riemann, B. C., Cottraux, J., O’Connor, K., Hale, L., Abramowitz, J., Fontenelle, L. F., & Storch, E. (2014). Musical obsessions: A comprehensive review of neglected clinical phenomena. Journal of Anxiety Disorders, 28, 580-58.

Tuerk, P. W., McGuire, J. F., & Piacentini, J. (2024). A randomized controlled trial of OC-go for childhood obsessive–compulsive disorder: augmenting homework compliance in exposure with response prevention treatment. Behavior Therapy, 55(2), 306-319.

van der Straten, A., Bruin, W., van de Mortel, L., ten Doesschate, F., Merkx, M. J., de Koning, P., Vulink, N., Figee, M., van den Heuvel, O. A., Denys, D., & van Wingen, G. (2024). Pharmacological and psychological treatment have common and specific effects on brain activity in obsessive-compulsive disorder. Depression and Anxiety, Vol 2024, 2024, ArtID 6687657, 2024.

Vigerland, S., Fredlander, S., Aspvall, K., Jolstedt, M., Lenhard, F., Mataix-Cols, D., Ljótsson, B., & Serlachius, E. (2024). Effectiveness of internet-delivered cognitive behavioural therapy for anxiety and obsessive-compulsive disorders within routine clinical care in rural Sweden. Internet Interventions, 36, 100738.

*Weidle, B., Ivarsson, T., Asbahr, F. R., Calvo, R., Mataix-Cols, D., Rynn, M. A., & Storch, E. A. (2021). Specialty knowledge and competency standards for pharmacotherapy for pediatric obsessive-compulsive disorder. Psychiatry Research, 299, 113858.